Cytology. Since the publication of the consensus guidelines, new cervical cancer screening guidelines have been published and new information has. ASCCP Guideline. HPV Unknown. HPV Positive*. Repeat Cytology. -. @ 12 mos. Cytology. @ 6 & 12 mos OR. HPV DNA Testing. @ 12 mos. ASC or HPV (+) —. Manage per. ASCCP Guideline. HPV Unknown. HPV Positive*. Repeat cytology. >> ASC or HPV (+) > Repeat Colposcopy. @ 12 mos cytology. @6& 12 mos OR.

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Now, providers who use cotesting will be receiving combinations of results, some of which will be discordant e.

This material may not otherwise be downloaded, copied, printed, stored, transmitted or reproduced in any medium, whether now known or later invented, except as authorized in writing by the AAFP. Terminology used for recommendations. Cervical adenocarcinoma and squamous cell carcinoma incidence trends among white women ssccp black women in the United States for — HPV infection is most prevalent among women 20 to 24 years of age, with a gradual decline in prevalence through 59 years of age.

Pregnancy does not accelerate cervical lesions, and cervical cancer occurs in only five ofpregnancies. Bethesda implementation aasccp reporting rates: Obstetric outcomes after conservative treatment for intraepithelial or early invasive cervical lesions: Human papillomavirus DNA detection algorlthm histological findings in women referred for atypical glandular cells or adenocarcinoma in situ in their Pap smears.

Managing women with unsatisfactory cytology and specimens missing endocervical or transformation zone components Category: Already a member or subscriber? Management algorithms and information on strength of recommendations and quality of evidence can be found at http: Women with no CIN2,3 at colposcopy should be observed with colposcopy and cytology every 6 months for up to two years, until 2 consecutive negative Pap tests are reported and no high-grade colposcopic abnormality is observed.


A,gorithm were developed by 1 conventional literature review and evidence weighting, and 2 risk-based assessment of various management strategies using observational data from KPNC. Should women with atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesion, receive reflex human papillomavirus-DNA testing? Currently there are no outcome data available to determine different management strategies when using the new LAST histopathology terminology.


What should I do? Obtaining a histologic specimen of the transformation zone and endocervical canal by laser or cold-knife conization or loop electrosurgical excision or conization.

Accuracy of the Papanicolaou test in screening for and follow-up of cervical cytologic abnormalities: Adenocarcinoma in situ of the algoritum Treatment during pregnancy is unacceptable unless invasive carcinoma is identified.

AIS is a high-grade glandular lesion that is relatively rare 0. Abnormal cervical cytology in pregnancy: Guidelines are intended for use only with HPV tests that have been analytically and clinically validated, as documented by Food and Drug Administration FDA licensing and approval or publication in peer-reviewed scientific literature Management based on results of HPV tests that have not been similarly validated may not result in outcomes intended by these guidelines and may increase the potential ascccp patient harm.

Results saccp data analysis of mass Papanicolaou screening ofwomen in the United States in In women with atypical squamous cells—cannot exclude high-grade squamous intraepithelial lesion ASC-Hthe prevalence of CIN 2,3 is as high as 50 percent.


However, even with negative cytology, older women who are HPV positive have a greater risk of developing CIN 3 within 10 years, compared with younger women Android, iPhone, iPad, Spanish Language. Clinical applications of HPV testing: Conservative management of adolescents with any cytologic or histologic diagnosis except specified cervical intraepithelial neoplasia, grade 3 and adenocarcinoma in situ is recommended. When CIN2 is found in young women, observation algorith, preferred but treatment alggorithm acceptable.

This suggests that less aggressive assessment will minimize potential harms of managing abnormalities likely to resolve spontaneously. Endometrial cells are found on 0. Management of women with low-grade squamous intraepithelial lesion.

Dysplasia associated with atypical glandular cells on cervical cytology [published correction appears in Obstet Gynecol.

Genital human papillomavirus infection: One of multiple options when data indicate another approach is superior or when no data favor any single option. Margin of any visible lesion and entire squamocolumnar junction are visible. Use of human papillomavirus DNA testing as an adjunct to cytology for cervical cancer screening in women 30 years and older.

More in Pubmed Citation Related Articles. ASCCP convened a steering committee and invited representatives from national professional organizations, government agencies, and advocacy organizations to participate in guidelines development.

Guidelines – ASCCP

Agency for Healthcare Research and Quality January Why new guidelines now? Bigras G, de Marval F. Arch Pathol Lab Med.

Screening for high-grade cervical intraepithelial neoplasia and cancer by testing for high-risk HPV, routine cytology or colposcopy.

N Engl J Med.