Lepra tuberculoide. Rios González, Carlos Miguel Cátedra de Dermatología. Facultad de Ciencias Médicas. Universidad Nacional de Caaguazú. Paraguay. El 65,4 % de los casos índices fueron hombres y 22 (84,6 %) lepromatosos; dos tenían lepra indeterminada y dos tuberculoide. Los casos secundarios fueron. La lepra o malaltia de Hansen és una malaltia infectocontagiosa però difícilment . que estaran engruixits i es podran palpar, sobretot a la lepra tuberculoide.

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From the ldpra point of view the greater evidence of pathology appears when the nasal bones, the nasal spine and even the midline maxillary region become affected; the erosion or complete destruction of the latter leads to tissue collapse, with sinking and spreading of the overlying skin and other soft tissues saddle nose.

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Lepromatous leprosy in index cases was more frequently associated with leprosy in the couple. Leprosy situation in the world and multidrug therapy coverage.

Involvement of male genitalia in leprosy. His skin was dry, pale and sclerotic. In addition to these polar forms of immune response, a significant number of patients show a partial or incomplete response and present borderline forms of the disease.

Disabilities were more common in the feet and to a higher degree in lepromatous index cases who had had the disease for a longer time than the secondary cases because these were more frequently paucibacillary patients who had a disease having shorter evolution. Similares no Google Citados no Tuberculoidf Scholar. The patient reported here suffered both bilateral blindness and leonine facies Figure 1. Depending on the stage at which they are diagnosed, the appearance of these lesions may be similar to those of other conditions and this tuberculoidw the differential diagnosis difficult 2,6, None of the couples had had leprosy at the time of being married.


Clinical exams were performed and personal interviews carried out with couples suffering from leprosy.

In addition to traumatic lesions, the loss of cutaneous tissue favours pyogenic infections, ulcers and spreading to deeper tissues. Leprous patients with a positive Mitsuda reaction usually present a histological tissue reaction similar to that found in tuberculosis, ruberculoide hence the name give to this clinical form is tuberculoid leprosy.

Lepra lepromatosa: Revisión y caso clínico

Smithsonian Institution Press; Multiple amputations bilateral metacarpophalangeal, left metatarsophalangeal and nose due to relapsing infection of the septum, performed during the active phase of the disease Figure 1 secondary to the leprous infection. Oral lesions in leprosy. En los pies, tubeeculoide pacientes lepromatosos presentaron discapacidad grado I y 5 tuvieron discapacidad grado II, tres lepromatosos y 2 tuberculoides.

A review and case report. In contrast, patients tuebrculoide a negative Mitsuda reaction show minimal resistance to the action of mycobacteria, which grow in a relatively unrestricted fashion and form large bacterial clusters that prove to be highly infectious. As these bacteria multiply more in cooler areas the pattern of infection is usually focussed on the skin, superficial cutaneous structures especially peripheral nervesthe eyes and the testicles.

Impact of leprosy on family and intimate tjberculoide. The circulating bacteria are so abundant that they can be detected in peripheral blood samples.


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The reason for the different immune response of the two clinical forms remains unclear. Our patient showed generalized changes in pigmentation, as can be seen in the figures.

Treatment is difficult as it must be continued for long periods, requires several drugs with adverse effects and proves very expensive, particularly for less developed countries. Lwpra, A, Stugh AM.

There may also be destruction of the anterior maxilla and loss of teeth 1,2,4,5. The facial skin shows areas of localized swelling, with deep furrows between them. Correlation of oral surface temperatures and the lesions of leprosy. Once signs have appeared the disease will generally progress slowly unless treated.

Hansen Neuropathy: Still a Possible Diagnosis in the Investigation of a Peripheral Neuropathy.

Laboratory studies suggest there to be a defective T-cell response to the antigens of M. Current Syntheses and Future Options. Rev Leprol Fontilles ; However, as positive results are also obtained in patients without leprosy this test only serves to assess the immunological state in already-diagnosed patients 1,6.

The disease presents polar clinical forms the “multibacillary” lepromatous leprosy and the “paucibacillary” tuberculoid leprosyas well as other intermediate forms with hybrid characteristics Table 1.

At some undetermined point the patient suffers an initial bacillaemia, which may be repeated through recurrent episodes or progress toward a continuous bacteraemia.